Cancer Death and Antihypertensive Drug Treatment—Response
نویسندگان
چکیده
منابع مشابه
Cancer death and antihypertensive drug treatment-response.
We wish to thank Drs. Goldstein and Mascitelli (1) for their careful reading of our article (2). In our introduction, we identified prior reports of the association of antihypertensive treatment with cancer and found the results from previous work to be equivocal. We are aware of the findings of PROSPER inwhich new cancer diagnoses were more frequent on pravastatin than on placebo (1.25, 1.04–1...
متن کاملCancer death and antihypertensive drug treatment-letter.
The increasing cancer-related mortality related to rapid decreases in blood pressure from the pharmacologic treatment of hypertension as seen in the Systolic Hypertension in the Elderly Program (SHEP; 1) draws interesting parallels to the PROspective Study of Pravastatin in the Elderly at Risk (PROSPER) trial (2). The data suggest that some common treatments used for the prevention of cardiovas...
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During 30 years of follow-up, there were 183 sadden deaths hi men and 77 hi women ages 35 to 94 years who participated hi the Framingham Study. Risk of sudden death was increased threefold in hypertensive persons but only if there was no previously diagnosed coronary heart disease. Men receiving antihypertensive treatment had more than twice the risk of sudden death compared with those who were...
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Adverse drug-drug interactions may occur when a major therapeutic mechanism of one drug class (such as bradycardia with a beta blocker) is excessively exaggerated by the addition of another heart-rate slowing antihypertensive, such as verapamil. The most important interactions at the molecular level are those of the hepatic enzyme, cytochrome (CYP) 3A4. A classic example is the inhibitory effec...
متن کاملPersistence to antihypertensive drug classes
The aim was to study persistence to, and switching between, antihypertensive drug classes and to determine factors associated with poor persistence.This was an observational cohort study. The Swedish Primary Care Cardiovascular Database includes data from medical records, socioeconomic data, filled prescriptions, and hospitalizations from national registries for 75,000 patients with hypertensio...
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ژورنال
عنوان ژورنال: Cancer Epidemiology Biomarkers & Prevention
سال: 2014
ISSN: 1055-9965,1538-7755
DOI: 10.1158/1055-9965.epi-14-0864